Description
【GS-441524 MECHANISM】
GS-441524 is s small molecule nucleoside analog that undergoes intracellular phosphorylation under the action of cellular kinases in vivo to produce active triphosphate metabolites (NTPs) that can compete with natural nucleotides in vivo, inhibits RNA polymerase, and interferes with cat infection RNA replication virus, thereby preventing the synthesis of feline infectious peritonitis virus
【Specification】15mg/mL, 20mg/mL
【usage】2.5-5.0 mg/kg.sc.q.24h. requires an experienced operator to avoid injecting the drug
to the same part of the dermis or subcutaneous layer.
【preservation】room temperature, avoid direct sunlight.
【course of treatment】usually after 5 days of use, symptoms are relieved, but due to the absence of more clinical data to indicate more the drug can be discontinued for a long time, and the medication time is decided by the doctor and the owner in consultation according to individual differences.
【precautions】
1. since this drug is still in the clinical stage, there are great differences in individual animals, and the treatment reported in the current literature is reported
the cure rate is only the result of a small number of animals, and the specific effect should be determined according to the animal’s situation
2. FOCUS ON COMPLICATIONS AND PREVENT SECONDARY INFECTIONS (MANY CATS DIE FROM COMPLICATIONS, NOT THE FIP ITSELF).
3. it is not recommended to use hormones (many steroid drugs will suppress the animal’s own immunity)
4. theoretically, it can be combined with interferons, but there is no specific experimental data.
